SFB 1456: Mathematics of Experiment

We witness an era where unprecedented amounts of data are acquired in experimental research in the natural sciences. While new measurement techniques and instruments keep being devised and improved for ...

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TRR 274: Checkpoints of Central Nervous System Recovery

The central nervous system (CNS) is a terminally differentiated tissue, where any insult carries a heightened risk - yet the tissue response to these insults is variable and can range ...

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ERC Advanced Grant "MitoCRISTAE"

Mitochondrial cristae biogenesis is an enigma ever since the first imaging of mitochondria, the ‘powerhouses’ of eukaryotic cells, by electron microscopy in the 1950s. The mitochondrial cristae, dynamic and structurally ...

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FOR 2848 "Nanoscale Architecture and Heterogeneity of the Mitochondrial Inner Membrane" Speaker: Stefan Jakobs

The inner membrane of mitochondria exhibits a unique three dimensional structure. This membrane is also exceptionally rich in proteins, most of which facilitate transport and catalytic processes. It is assumed ...

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SFB 1286 "Quantitative Synaptology"

Synapses are the central information processors in the brain. Their function, efficacy and plasticity are key determinants of all brain functions, and of the corresponding behavioral output. Conversely, aberrant synapse ...

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SFB 1190 "Compartmental Gates and Contact Sites in Cells"

The compartmentalization of cells ensures a highly specific distribution of nucleic acids, proteins and metabolites. At the same time, intracellular compartments must communicate and exchange molecules. Two major systems enable ...

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EXC 2067 "Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells"

Disorders of the heart and the brain are leading causes of disability and death. The electrically excitable cells of these widely distinct organs, cardiomyocytes and neurons, have surprisingly many physiological ...

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