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The press about us:

Ein Auge für Details. Artikel in der Apotheken Umschau  (01.09.2016)

Reversibel schaltbare fluoreszierende Proteine für die Superauflösung. BIOspektrum  (27.06.2016)

Türöffner für den Selbstmord. Göttinger Tageblatt (20.01.2016)

Ein Trick macht Blick in lebende Zellen möglich. Göttinger Tageblatt (09.12.2011)

Mikroskopie: Liveschaltung ins Mäusehirn. Spiegel (05.02.2010)

3-D-Mikroskopie: Forscher fotografieren das Innere der Zellkraftwerke. Spiegel Online (28.05.2009)


Stephan, T., Roesch, A., Riedel, D., Jakobs, S.: "Live-cell STED nanoscopy of mitochondrial cristae"
Scientific Reports 9, pp: 12419. DOI 10.1038/s41598-019-48838-2. Access the Publication via Access the Publication via SN SharedItDetails

Wurm, C.A., Schwarz, H., Jans, D.C., Riedel, D., Humbel, B.M., Jakobs, S.: "Correlative STED super-resolution light and electron microscopy on resin sections"
Journal of Physics D: Applied Physics 52 (37). DOI 10.1088/1361-6463/ab2b31Details

Frahm, L., Keller-Findeisen, J., Alt, P., Schnorrenberg, S., del Alamo Ruiz, M., Aspelmeier, T., Munk, A., Jakobs, S., Hell, S.W.: "Molecular contribution function in RESOLFT nanoscopy"
Optics Express 27 (15), 21956-21987. DOI 10.1364/OE.27.021956Details

Ramos, E.S., Motori, E., Brüser, C., Kühl, I., Yeroslaviz, A., Ruzzenente, B., Kauppila, J.H., Busch, J.D., Hultenby, K., Habermann, B.H., Jakobs, S., Larsson, N.G., Mourier, A.: "Mitochondrial fusion is required for regulation of mitochondrial DNA replication"
PLOS Genetics 15 (6), e1008085. DOI 10.1371/journal.pgen.1008085Details

Stephan, T., Roesch, A., Riedel, D., Jakobs, S.: "Live-cell STED microscopy of mitochondrial cristae"
BioRxiv. DOI 10.1101/640920Details

Callegari, S., Müller, T., Schulz, C., Lenz, C., Jans, D.C., Wissel, M., Opazo, F., Rizzoli, S.O., Jakobs, S., Urlaub, H., Rehling, P., Deckers, M.: "A MICOS-TIM22 Association Promotes Carrier Import into Human Mitochondria."
Journal of Molecular Biology, in early view. DOI 10.1016/j.jmb.2019.05.015Details

Stold, S., Stephan, T., Jans, D.C., Brüser, C., Lange, F., Keller-Findeisen, J., Riedel, D., Hell, S.W., and Jakobs, S.: "Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria"
PNAS 116 (20), 9853-9858. DOI 10.1073/pnas.1820364116Details

Tuijtel, M.W., Koster, A.J., Jakobs, S., Faas, F.G.A., Sharp, T.H.: "Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins"
Scientific Reports 9, pp: 1369. DOI 10.1038/s41598-018-37728-8Details

Richter, F., Dennerlein, S., Nikolov, M., Jans, D.J., Naumenko, N., Aich, A., MacVicar, T., Linden, A., Jakobs, S., Urlaub, H., Langer, T., Rehling, P.: "ROMO1 is a constituent of the human presequence translocase required for YME1L protease import"
Journal of Cell Biology, in early view. DOI 10.1083/jcb.201806093Details


Kamper, M., Ta, H., Jensen, N.A., Hell, S.W., & Jakobs, S.: "Near-infrared STED nanoscopy with an engineered bacterial phytochrome"
Nature Communications 9, 4762. DOI 10.1038/s41467-018-07246-2. Access the Publication via Access the Publication via SN SharedItDetails

Stoldt, S., Wenzel, D., Kehrein, K., Riedel, D., Ott, M., & Jakobs, S.: "Spatial orchestration of mitochondrial translation and OXPHOS complex assembly"
Nature Cell Biology 20, 528–534. DOI 10.1038/s41556-018-0090-7. Access the Publication via Access the Publication via SN SharedIt Comment in Nature Cell Biology.Details

Butkevich, A.N., Ta, H., Ratz, M., Stoldt, S., Jakobs, S., Belov, V.N., Hell, S.W.: "Two-Color 810 nm STED Nanoscopy of Living Cells with Endogenous SNAP-Tagged Fusion Proteins."
ACS Chemical Biology 13 (2), 475 - 480. DOI 10.1021/acschembio.7b00616Details

Faoro, F., Bassu, M., Mejia, Y.X., Stephan, T., Dudani, N., Boeker, S., Jakobs, S. & Burg, T.P.: "Aberration-corrected cryoimmersion light microscopy"
PNAS 115 (6), 1204 - 1209. DOI 10.1073/pnas.1717282115 Details

Coquelle, N., Sliwa, M., Woodhouse, J., Schiro, G., Adam, V., Aquila, A., Barends, T., Boutet, S., Byrdin, M., Carbajo, S., de la Mora, E., Doak, Feliks, M., Fieschi, F., Foucar, L., Guillon, V., Hilpert, M., Hunter, M., Jakobs, S., Koglin, J., Kovacsova, G., Lane, T., Lévy, B., Liang, M., Nass, K., Ridard, J., Robinson, J., Roome, C., Ruckebusch, C., Seaberg, M., Thepaut, M., Cammarata, M., Demac: "Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography"
Nature Chemistry 10, 31-37. DOI 10.1038/nchem.2853Details


Sahl, S.J., Hell, S.W. & Jakobs, S. : "Fluorescence nanoscopy in cell biology"
Nature Reviews Molecular Cell Biology 18, 685-701. DOI 10.1038/nrm.2017.71 . Access the Publication via Access the Publication via SN SharedItDetails

Tarasenko, D., Barbot, M., Jans, D.C., Kroppen, B., Sadowski, B., Heim, G., Möbius, W., Jakobs, S., Meinecke, M.: "The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology"
Journal of Cell Biology 216 (4), 889-899. DOI 10.1083/jcb.201609046Details

Chmyrov, A., Leutenegger, M., Grotjohann, T., Schönle, A., Keller-Findeisen, J., Kastrup, L., Jakobs, S., Donnert, G., Sahl, S.J., and Hell, S.W.: "Achromatic light patterning and improved image reconstruction for parallelized RESOLFT nanoscopy"
Scientific Reports 7, pp: 44619. DOI 10.1038/srep44619Details


Sahl, S.J., Balzarotti, F., Keller-Findeisen, J., Leutenegger, M., Westphal, V., Egner, A., Lavoie-Cardinal, F., Chmyrov, A., Grotjohann, T., Jakobs, S.: "Comment on “Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics”"
Science 352 (6285), 527 pp.. DOI 10.1126/science.aad7983Details

Schnorrenberg S., Grotjohann T., Vorbrüggen G., Herzig A., Hell S., Jakobs S.: "In vivo super-resolution RESOLFT microscopy of Drosophila melanogaster"
eLIFE 5, e15567. DOI 10.7554/eLife.15567. Highlighted in Nature Methods.Details

Chmyrov, A. , Leutenegger, M., Grotjohann, T., Schoenle, A., Keller-Findeisen, J., Kastrup, L., Jakobs, S., Donnert, G., Sahl, S.J., Hell, S.W.: "Achromatic light patterning and improved image reconstruction for parallelized RESOLFT nanoscopy" Link to Online PublicationDetails

Callegari, S., Richter, F., Chojnacka, K., Jans, D.C., Lorenzi, I., Pacheu-Grau, D., Jakobs, S., Lenz, C., Urlaub, H., Dudek, J., Chacinska, A., and Rehling, P.: "TIM29 is a subunit of the human carrier translocase required for protein transport"
FEBS Letters 590 (23), 4147–4158. DOI 10.1002/1873-3468.12450Details


Walter, A., Andresen, M., Jakobs, S., Schroeder, J., Schwarzer, D.: "Primary Light-Induced Reaction Steps of Reversibly Photoswitchable Fluorescent Protein Padron0.9 Investigated by Femtosecond Spectroscopy"
J. Phys. Chem. B. 119 (16), 5136–5144. DOI 10.1021/jp512610qDetails

Kehrein, K., Schilling, R., Möller-Hergt, B.V., Wurm, C.A., Jakobs, S., Lamkemeyer,T., Langer, T., Ott, M.: "Organization of Mitochondrial Gene Expression in Two Distinct Ribosome-Containing Assemblies"
Cell Reports, 10 (6), 843–853. DOI 10.1016/j.celrep.2015.01.012Details

Ratz, M., Testa, I., Hell, S.W., Jakobs, S.: "CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells"
Scientific Reports 5, pp: 9592. DOI 10.1038/srep09592. This publication is one of the Top 100 read Scientific Reports articles in 2015! Access the recommendation on F1000PrimeDetails

Kukat C, Davies KM, Wurm CA, Spåhr H, Bonekamp NA, Kühl I, Joos F, Polosa PL, Park CB, Posse V, Falkenberg M, Jakobs S, Kühlbrandt W, Larsson NG: "Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid."
PNAS 112 (36), 11288-93. DOI 10.1073/pnas.1512131112Details

Dennerlein S, Oeljeklaus S, Jans D, Hellwig C, Bareth B, Jakobs S, Deckers M, Warscheid B, Rehling P.: "MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly."
Cell Reports 12 (10), 1644-55. DOI 10.1016/j.celrep.2015.08.009Details

Duwé S, De Zitter E, Gielen V, Moeyaert B, Vandenberg W, Grotjohann T, Clays K, Jakobs S, Van Meervelt L, Dedecker P.: "Expression-Enhanced Fluorescent Proteins Based on Enhanced Green Fluorescent Protein (EGFP) for Super-Resolution Microscopy."
ACS Nano 10, 9528–9541. DOI 10.1021/acsnano.5b04129Details

Ilgen, P., Grotjohann, T., Jans, D.C., Kilisch, M., Hell, S.W., Jakobs,S.: "RESOLFT Nanoscopy of Fixed Cells Using a Z-Domain Based Fusion Protein for Labelling."
PLoS One 10(9) ( e0136233). DOI 10.1371/journal.pone.0136233Details

Sakowska P, Jans DC, Mohanraj K, Riedel D, Jakobs S, Chacinska A: "The oxidation status of Mic19 regulates MICOS assembly."
Mol Cell Biol. 35 (24), 4222-4237. DOI 10.1128/MCB.00578-15Details

Hell, S.W., Sahl, S.J., Bates, M., Zhuang, X., Heintzmann, R., Booth, M.J., Bewersdorf, J., Shtengel, G., Hess, H., Tinnefeld, P., Honigmann, A., Jakobs, S., Testa, I., Cognet, L., Lounis, B., Ewers,H., Davis, S.J., Eggeling, C., Klenerman, D., Willig, K.I., Vicidomini, G., Castello, M.: "The 2015 super-resolution microscopy roadmap"
Journal of Physics D: Applied Physics 48 (443001). DOI doi:10.1088/0022-3727/48/44/443001Details


Jensen, N.A.,Danzl, J.G.,Willig, K.I.,Lavoie-Cardinal, F.,Brakemann, T.,Hell, S.W. and Jakobs, S.: "Coordinate-Targeted and Coordinate-Stochastic Super-Resolution Microscopy with the Reversibly Switchable Fluorescent Protein Dreiklang"
ChemPhysChem 15 (4), 756-762. DOI 10.1002/cphc.201301034Details

Lavoie-Cardinal, F.,Jensen, N.A.,Westphal, V.,Stiel, A.C.,Chmyrov, A.,Bierwagen, J.,Testa, I.,Jakobs, S. and Hell, S.W.: "Two-Color RESOLFT Nanoscopy with Green and Red Fluorescent Photochromic Proteins"
ChemPhysChem 15 (4), 655-663. DOI 10.1002/cphc.201301016. Journal Cover ChemPhysChem Mar. 2014.Details

Pfanner, N.,van der Laan, M.,Amati, P.,Capaldi, R.A.,Caudy, A.A.,Chacinska, A.,Darshi, M.,Deckers, M.,Hoppins, S.,Icho, T.,Jakobs, S.,Ji, J.,Kozjak-Pavlovic, V.,Meisinger, C.,Odgren, P.R.,Park, S.K.,Rehling, P.,Reichert, A.S.,Sheikh, M.S.,Taylor, S.S.,Tsuchida, N.,van der Bliek, A.M.,van der Klei, I.J.,Weissman, J.S.,Westermann, B.,Zha, J.,Neupert, W. and Nunnari, J.: "Uniform nomenclature for the mitochondrial contact site and cristae organizing system"
J. Cell Biol. 204 (7), 1083-1086. DOI 10.1083/jcb.201401006Details

Ilgen P., Stoldt S., Conradi LC., Wurm CA., Rüschoff J., Ghadimi BM., Liersch T., Jakobs S.: "STED Super-Resolution Microscopy of Clinical Paraffin-Embedded Human Rectal Cancer Tissue"
PLoS ONE (9), e101563. DOI 10.1371/journal.pone.0101563Details

Stefan Geissbuehler, Azat Sharipov, Aurélien Godinat, Noelia L. Bocchio, Patrick A. Sandoz, Anja Huss, Nickels A. Jensen, Stefan Jakobs, Jörg Enderlein, F. Gisou van der Goot, Elena A. Dubikovskaya, Theo Lasser, Marcel Leutenegger: "Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging"
Nature Communications (5) (5830). DOI 10.1038/ncomms6830Details


Jans, D.C.,Wurm, C.A.,Riedel, D.,Wenzel, D.,Stagge, F.,Deckers, M.,Rehling, P. and Jakobs, S.: "STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria"
PNAS 110 (22), 8936-8941. DOI 10.1073/pnas.1301820110Details


Alkhaja, A.K.,Jans, D.C.,Nikolov, M.,Vukotic, M.,Lytovchenko, O.,Ludewig, F.,Schliebs, W.,Riedel, D.,Urlaub, H.,Jakobs, S. and Deckers, M.: "MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization"
Mol. Biol. Cell 23 (2), 247-257. DOI 10.1091/mbc.E11-09-0774Details

Grotjohann, T.,Testa, I.,Reuss, M.,Brakemann, T.,Eggeling, C.,Hell, S.W. and Jakobs, S.: "rsEGFP2 enables fast RESOLFT nanoscopy of living cells"
ELife 1, e00248. DOI 10.7554/eLife.00248. Highlighted in The Scientist.Details

Kolmakov, K.,Wurm, C.A.,Hennig, R.,Rapp, E.,Jakobs, S.,Belov, V.N. and Hell, S.W.: "Red-Emitting Rhodamines with Hydroxylated, Sulfonated, and Phosphorylated Dye Residues and Their Use in Fluorescence Nanoscopy"
Chem. Eur. J. 18 (41), 12986-12998. DOI 10.1002/chem.201201168Details

Stoldt, S.,Wenzel, D.,Hildenbeutel, M.,Wurm, C.A.,Herrmann, J.M. and Jakobs, S.: "The inner-mitochondrial distribution of Oxa1 depends on the growth conditions and on the availability of substrates"
Mol. Biol. Cell 23 (12), 2292-2301. DOI 10.1091/mbc.E11-06-0538Details

Testa, I.,Urban, N.T.,Jakobs, S.,Eggeling, C.,Willig, K.I. and Hell, S.W.: "Nanoscopy of Living Brain Slices with Low Light Levels"
Neuron 75 (6), 992-1000. DOI 10.1016/j.neuron.2012.07.028Details

Vukotic, M.,Oeljeklaus, S.,Wiese, S.,Voegtle, F.N.,Meisinger, C.,Meyer, H.E.,Zieseniss, A.,Katschinski, D.M.,Jans, D.C.,Jakobs, S.,Warscheid, B.,Rehling, P. and Deckers, M.: "Rcf1 Mediates Cytochrome Oxidase Assembly and Respirasome Formation, Revealing Heterogeneity of the Enzyme Complex"
Cell Metab. 15 (3), 336-347. DOI 10.1016/j.cmet.2012.01.016. Highlighted in Cell Metabolism.Details


Brakemann, T.,Stiel, A.C.,Weber, G.,Andresen, M.,Testa, I.,Grotjohann, T.,Leutenegger, M.,Plessmann, U.,Urlaub, H.,Eggeling, C.,Wahl, M.C.,Hell, S.W. and Jakobs, S.: "A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching"
Nature Biotech. 29 (10), 942-947. DOI 10.1038/nbt.1952. Highlighted in Nature Biotechnoloy. Journal Cover Nature Biotechnology Oct. 2011. Access the recommendation on F1000PrimeDetails

Grotjohann, T.,Testa, I.,Leutenegger, M.,Bock, H.,Urban, N.T.,Lavoie-Cardinal, F.,Willig, K.I.,Eggeling, C.,Jakobs, S. and Hell, S.W.: "Diffraction-unlimited all-optical imaging and writing with a photochromic GFP"
Nature 478 (7368), 204-208. DOI 10.1038/nature10497. Access the recommendation on F1000PrimeDetails

Jakobs, S.,Stoldt, S. and Neumann, D.: "Light Microscopic Analysis of Mitochondrial Heterogeneity in Cell Populations and Within Single Cells"
High Resolution Microbial Single Cell Analytics 124, 1-19. DOI 10.1007/10_2010_81Details

Kleine-Vehn, J.,Wabnik, K.,Martiniere, A.,Langowski, L.,Willig, K.,Naramoto, S.,Leitner, J.,Tanaka, H.,Jakobs, S.,Robert, S.,Luschnig, C.,Govaerts, W.,Hell, S.W.,Runions, J. and Friml, J.: "Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane"
Mol. Syst. Biol. 7, 540. DOI 10.1038/msb.2011.72Details

Kukat, C.,Wurm, C.A.,Spahr, H.,Falkenberg, M.,Larsson, N.-G. and Jakobs, S.: "Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA"
PNAS 108 (33), 13534-13539. DOI 10.1073/pnas.1109263108Details

Willig, K.I.,Stiel, A.C.,Brakemann, T.,Jakobs, S. and Hell, S.W.: "Dual-Label STED Nanoscopy of Living Cells Using Photochromism"
Nano Lett. 11 (9), 3970-3973. DOI 10.1021/nl202290wDetails

Wurm, C.A.,Neumann, D.,Lauterbach, M.A.,Harke, B.,Egner, A.,Hell, S.W. and Jakobs, S.: "Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient"
PNAS 108 (33), 13546-13551. DOI 10.1073/pnas.1107553108Details


Bierwagen, J.,Testa, I.,Foelling, J.,Wenzel, D.,Jakobs, S.,Eggeling, C. and Hell, S.W.: "Far-Field Autofluorescence Nanoscopy"
Nano Lett. 10 (10), 4249-4252. DOI 10.1021/nl1027638Details

Brakemann, T.,Weber, G.,Andresen, M.,Groenhof, G.,Stiel, A.C.,Trowitzsch, S.,Eggeling, C.,Grubmueller, H.,Hell, S.W.,Wahl, M.C. and Jakobs, S.: "Molecular Basis of the Light-driven Switching of the Photochromic Fluorescent Protein Padron"
J. Biol. Chem. 285 (19), 14603-14609. DOI 10.1074/jbc.M109.086314Details

Hein, B.,Willig, K.I.,Wurm, C.A.,Westphal, V.,Jakobs, S. and Hell, S.W.: "Stimulated Emission Depletion Nanoscopy of Living Cells Using SNAP-Tag Fusion Proteins"
Biophys. J. 98 (1), 158-163. DOI 10.1016/j.bpj.2009.09.053Details

Mitronova, G.Y.,Belov, V.N.,Bossi, M.L.,Wurm, C.A.,Meyer, L.,Medda, R.,Moneron, G.,Bretschneider, S.,Eggeling, C.,Jakobs, S. and Hell, S.W.: "New Fluorinated Rhodamines for Optical Microscopy and Nanoscopy"
Chem. Eur. J. 16 (15), 4477-4488. DOI 10.1002/chem.200903272Details

Neumann, D.,Buckers, J.,Kastrup, L.,Hell, S.W. and Jakobs, S.: "Two-color STED microscopy reveals different degrees of colocalization between hexokinase-I and the three human VDAC isoforms"
PMC Biophys. 3 (4). DOI 10.1186/1757-5036-3-4Details

Testa, I.,Wurm, C.A.,Medda, R.,Rothermel, E.,von Middendorf, C.,Foelling, J.,Jakobs, S.,Schoenle, A.,Hell, S.W. and Eggeling, C.: "Multicolor Fluorescence Nanoscopy in Fixed and Living Cells by Exciting Conventional Fluorophores with a Single Wavelength"
Biophys. J. 99 (8), 2686-2694. DOI 10.1016/j.bpj.2010.08.012Details

Wurm, C.A.,Neumann, D.,Schmidt, R.,Egner, A. and Jakobs, S.: "Sample Preparation for STED Microscopy"
Live Cell Imaging: Methods and Protocols 591, 185-199. DOI 10.1007/978-1-60761-404-3_11Details


Suppanz, I.E.,Wurm, C.A.,Wenzel, D. and Jakobs, S.: "The m-AAA Protease Processes Cytochrome c Peroxidase Preferentially at the Inner Boundary Membrane of Mitochondria"
Mol. Biol. Cell 20 (2), 572-580. DOI 10.1091/mbc.E07-11-1112Details


Altmann, K.,Frank, M.,Neumann, D.,Jakobs, S. and Westermann, B.: "The class V myosin motor protein, Myo2, plays a major role in mitochondrial motility in Saccharomyces cerevisiae"
J. Cell Biol. 181 (1), 119-130. DOI 10.1083/jcb.200709099. Access the recommendation on F1000PrimeDetails

Andresen, M.,Stiel, A.C.,Foelling, J.,Wenzel, D.,Schoenle, A.,Egner, A.,Eggeling, C.,Hell, S.W. and Jakobs, S.: "Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy"
Nature Biotech. 26 (9), 1035-1040. DOI 10.1038/nbt.1493. Highlighted in Nature Methods and Nature Chemical Biology. Access the recommendation on F1000PrimeDetails

Foelling, J.,Bossi, M.,Bock, H.,Medda, R.,Wurm, C.A.,Hein, B.,Jakobs, S.,Eggeling, C. and Hell, S.W.: "Fluorescence nanoscopy by ground-state depletion and single-molecule return"
Nature Meth. 5 (11), 943-945. DOI 10.1038/nmeth.1257Details

Stiel, A.C.,Andresen, M.,Bock, H.,Hilbert, M.,Schilde, J.,Schoenle, A.,Eggeling, C.,Egner, A.,Hell, S.W. and Jakobs, S.: "Generation of monomeric reversibly switchable red fluorescent proteins for far-field fluorescence nanoscopy"
Biophys. J. 95 (6), 2989-2997. DOI 10.1529/biophysj.108.130146. Highlighted in Nature Methods.Details

Testa, I.,Schoenle, A.,Middendorff, C.V.,Geisler, C.,Medda, R.,Wurm, C.A.,Stiel, A.C.,Jakobs, S.,Bossi, M.,Eggeling, C.,Hell, S.W. and Egner, A.: "Nanoscale separation of molecular species based on their rotational mobility"
Opt. Express 16 (25), 21093-21104. DOI 10.1364/oe.16.021093Details


Andresen, M.,Stiel, A.C.,Trowitzsch, S.,Weber, G.,Eggeling, C.,Wahl, M.C.,Hell, S.W. and Jakobs, S.: "Structural basis for reversible photoswitching in Dronpa"
PNAS 104 (32), 13005-13009. DOI 10.1073/pnas.0700629104Details

Bock, H.,Geisler, C.,Wurm, C.A.,Von Middendorff, C.,Jakobs, S.,Schoenle, A.,Egner, A.,Hell, S.W. and Eggeling, C.: "Two-color far-field fluorescence nanoscopy based on photoswitchable emitters"
Appl. Phys. B: Lasers Opt 88 (2), 161-165. DOI 10.1007/s00340-007-2729-0Details

Donnert, G.,Keller, J.,Wurm, C.A.,Rizzoli, S.O.,Westphal, V.,Schoenle, A.,Jahn, R.,Jakobs, S.,Eggeling, C. and Hell, S.W.: "Two-color far-field fluorescence nanoscopy"
Biophys. J. 92 (8), L67-L69. DOI 10.1529/biophysj.107.104497. Access the recommendation on F1000PrimeDetails

Eggeling, C.,Hilbert, M.,Bock, H.,Ringemann, C.,Hofmann, M.,Stiel, A.C.,Andresen, M.,Jakobs, S.,Egner, A.,Schoenle, A. and Hell, S.W.: "Reversible photoswitching enables single-molecule fluorescence fluctuation Spectroscopy at high molecular concentration"
Microsc. Res. Tech. 70 (12), 1003-1009. DOI 10.1002/jemt.20505Details

Egner, A.,Geisler, C.,Von Middendorff, C.,Bock, H.,Wenzel, D.,Medda, R.,Andresen, M.,Stiel, A.C.,Jakobs, S.,Eggeling, C.,Schoenle, A. and Hell, S.W.: "Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters"
Biophys. J. 93 (9), 3285-3290. DOI 10.1529/biophysj.107.112201Details

Meuer, K.,Suppanz, I.E.,Lingor, P.,Planchamp, V.,Goericke, B.,Fichtner, L.,Braus, G.H.,Dietz, G.P.H.,Jakobs, S.,Baehr, M. and Weishaupt, J.H.: "Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis"
Cell Death Differ. 14 (4), 651-661. DOI 10.1038/sj.cdd.4402087Details

Schwentker, M.A.,Bock, H.,Hofmann, M.,Jakobs, S.,Bewersdorf, J.,Eggeling, C. and Hell, S.W.: "Wide-field subdiffraction RESOLFT microscopy using fluorescent protein photoswitching"
Microsc. Res. Tech. 70 (3), 269-280. DOI 10.1002/jemt.20443Details

Stiel, A.C.,Trowitzsch, S.,Weber, G.,Andresen, M.,Eggeling, C.,Hell, S.W.,Jakobs, S. and Wahl, M.C.: "1.8 angstrom bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants"
Biochem. J. 402, 35-42. DOI 10.1042/bj20061401Details


Medda, R.,Jakobs, S.,Hell, S.W. and Bewersdorf, J.: "4Pi microscopy of quantum dot-labeled cellular structures"
J. Struct. Biol. 156 (3), 517-523. DOI 10.1016/j.jsb.2006.08.013Details

Schauss, A.C.,Bewersdorf, J. and Jakobs, S.: "Fis1p and Caf4p, but not Mdv1p, determine the polar localization of Dnm1p clusters on the mitochondrial surface"
J.Cell Sci. 119 (15), 3098-3106. DOI 10.1242/jcs.03026Details

Willig, K.I.,Kellner, R.R.,Medda, R.,Hein, B.,Jakobs, S. and Hell, S.W.: "Nanoscale resolution in GFP-based microscopy"
Nature Meth. 3 (9), 721-723. DOI 10.1038/nmeth922Details

Wurm, C.A. and Jakobs, S.: "Differential protein distributions define two sub-compartments of the mitochondrial inner membrane in yeast"
FEBS Letters 580 (24), 5628-5634. DOI 10.1016/j.febslet.2006.09.012Details


Andresen, M.,Wahl, M.C.,Stiel, A.C.,Grater, F.,Schafer, L.V.,Trowitzsch, S.,Weber, G.,Eggeling, C.,Grubmuller, H.,Hell, S.W. and Jakobs, S.: "Structure and mechanism of the reversible photoswitch of a fluorescent protein"
PNAS 102 (37), 13070-13074. DOI 10.1073/pnas.0502772102Details

Dimmer, K.S.,Jakobs, S.,Vogel, F.,Altmann, K. and Westermann, B.: "Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast"
J. Cell Biol. 168 (1), 103-115. DOI 10.1083/jcb.200410030. Access the recommendation on F1000PrimeDetails

Hofmann, M.,Eggeling, C.,Jakobs, S. and Hell, S.W.: "Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins"
PNAS 102 (49), 17565-17569. DOI 10.1073/pnas.0506010102. Access the recommendation on F1000PrimeDetails


Andresen, M.,Schmitz-Salue, R. and Jakobs, S.: "Short tetracysteine tags to beta-tubulin demonstrate the significance of small labels for live cell imaging"
Mol. Biol. Cell 15 (12), 5616-5622. DOI 10.1091/mbc.E04-06-0454Details

Gugel, H.,Bewersdorf, J.,Jakobs, S.,Engelhardt, J.,Storz, R. and Hell, S.W.: "Cooperative 4Pi excitation and detection yields sevenfold sharper optical sections in live-cell microscopy"
Biophys. J. 87 (6), 4146-4152. DOI 10.1529/biophysj.104.045815Details


Hell, S.W.,Jakobs, S. and Kastrup, L.: "Imaging and writing at the nanoscale with focused visible light through saturable optical transitions"
Appl. Phys. A 77 (7), 859-860. DOI 10.1007/s00339-003-2292-4Details

Jakobs, S.,Martini, N.,Schauss, A.C.,Egner, A.,Westermann, B. and Hell, S.W.: "Spatial and temporal dynamics of budding yeast mitochondria lacking the division component Fis1p"
J. Cell Sci. 116 (10), 2005-2014. DOI 10.1242/jcs.00423Details

Jakobs, S.,Schauss, A.C. and Hell, S.W.: "Photoconversion of matrix targeted GFP enables analysis of continuity and intermixing of the mitochondrial lumens"
FEBS Letters 554 (1-2), 194-200. DOI 10.1016/s0014=5793(03)01170-0Details

Messerschmitt, M.,Jakobs, S.,Vogel, F.,Fritz, S.,Dimmer, K.S.,Neupert, W. and Westermann, B.: "The inner membrane protein Mdm33 controls mitochondrial morphology in yeast"
J. Cell Biol. 160 (4), 553-564. DOI 10.1083/jcb.200211113. Access the recommendation on F1000PrimeDetails


Egner, A.,Jakobs, S. and Hell, S.W.: "Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast"
PNAS 99 (6), 3370-3375. DOI 10.1073/pnas.052545099Details

Kano, H.,Jakobs, S.,Nagorni, M. and Hell, S.W.: "Dual-color 4Pi-confocal microscopy with 3D-resolution in the 100 nm range"
Ultramicroscopy 90 (2-3), 207-213. DOI 10.1016/s0304-3991(01)00132-2Details



Dyba, M.,Klar, T.A.,Jakobs, S. and Hell, S.W.: "Ultrafast dynamics microscopy"
Appl. Phys. Lett. 77 (4), 597-599. DOI 10.1063/1.127056Details

Jakobs, S.,Subramaniam, V.,Schonle, A.,Jovin, T.M. and Hell, S.W.: "EGFP and DsRed expressing cultures of Escherichia coli imaged by confocal, two-photon and fluorescence lifetime microscopy"
FEBS Letters 479 (3), 131-135. DOI 10.1016/s0014-5793(00)01896-2Details

Klar, T.A.,Jakobs, S.,Dyba, M.,Egner, A. and Hell, S.W.: "Fluorescence microscopy with diffraction resolution barrier broken by stimulated emission"
PNAS 97 (15), 8206-8210. DOI 10.1073/pnas.97.15.8206. Highlighted in PNAS.Details