2024
Scholz J., Stephan T., Pérez A. G., Csiszár A., Hersch N., Fischer L. S., Brühmann S., Körber S., Litschko C., Mijanovic L., Kaufmann T., Lange F., Springer R., Pich A., Jakobs S., Peckham M., Tarantola M., Grashoff C., Merkel R., Faix J.: "Decisive role of mDia-family formins in cell cortex function of highly adherent cells"
Sci Adv. 10 (44), eadp5929. DOI 10.1126/sciadv.adp5929Details
Sahl S. J., Matthias J., Inamdar K., Weber M., Khan T. A., Brüser C., Jakobs S., Becker S., Griesinger C., Broichhagen J., Hell S. W.: "Direct optical measurement of intramolecular distances with angstrom precision"
Science 386 (6718), 180-187. DOI 10.1126/science.adj7368Details
Reshetniak S., Bogaciu C. A., Bonn S., Brose N., Cooper B. H., D'Este E., Fauth M., Fernández-Busnadiego R., Fiosins M., Fischer A., Georgiev S. V., Jakobs S., Klumpp S., Köster S., Lange F., Lipstein N., Macarrón-Palacios V., Milovanovic D., Moser T., Müller M., Opazo F., Outeiro T. F., Pape C., Priesemann V., Rehling P., Salditt T., Schlüter O., Simeth N., Steinem C., Tchumatchenko T., et al: "The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function"
J. Physiol.. DOI 10.1113/JP286400Details
Stephan T.*, Ilgen P., Jakobs S.*: "Visualizing mitochondrial dynamics at the nanoscale"
Light Sci Appl 13 (244). DOI 10.1038/s41377-024-01582-3. (*shared corresponding authors)Details
Aich A., Boshnakovska A., Witte S., Gall T., Unthan-Fechner K., Yousefi R., Chowdhury A., Dahal D., Methi A., Kaufmann S., Silbern I., Prochazka J., Nichtova Z., Palkova M., Raishbrook M., Koubkova G., Sedlacek R., Tröder S. E., Zevnik B., Riedel D., Michanski S., Möbius W., Ströbel P., Lüchtenborg C., Giavalisco P., Urlaub H., Fischer A., Brügger B., Jakobs S., Rehling P.: "Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver"
Nat. Commun. 15 (1), 6914. DOI 10.1038/s41467-024-51109-yDetails
Schweighofer S. V., Inamdar K., Jans D. C.*, Jakobs S.*: "STED super-resolution microscopy of mitochondrial translocases"
Methods Enzymol. 2024 707, 299-327. DOI 10.1016/bs.mie.2024.07.052. (*shared corresponding authors)Details
Weber M., Leutenegger M., Stoldt S., Jakobs S., Mihaila T. S., Butkevich A. N., Hell S. W.: "MINSTED fluorescence localization and nanoscopy"
bioRxiv. DOI 10.1101/2020.10.31.363424Details
Naas J., Nies G., Li H., Stoldt S., Schmitzer B., Jakobs S., Munk A.: "MultiMatch: geometry-Informed colocalization in multi-color super-resolution microscopy"
Commun Biol. 7 (1), 1139. DOI 10.1038/s42003-024-06772-8Details
Preminger N., Zucker B., Hassdenteufel S., Stephan T., Jakobs S., Kozlov M. M., Schuldiner M.: "Mitochondrial inner membrane remodeling as a driving force of organelle shaping"
bioRxiv. DOI 10.1101/2024.05.27.595707Details
Saleem H. N., Ignatyeva N., Stuut C., Jakobs S., Habeck M., Ebert A.: "3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models"
Cells 13 (11), 923. DOI 10.3390/cells13110923Details
Chen J., Stephan T., Gaedke F., Liu T., Li Y., Schauss A., Chen P., Wulff V., Jakobs S., Jüngst C. and Chen Z.: "An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells"
PNAS 121 (19), e2317703121. DOI 10.1073/pnas.2317703121Details
Oleksiievets N., Mougios N., Jans D. C., Hauke L., Thiele J. C., Basak S., Jakobs S., Opazo F., Enderlein J., Tsukanov R.: "Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT"
bioRxiv. DOI 10.1101/2024.04.02.587536Details
Schweighofer S. V., Jans D. C., Keller-Findeisen J., Folmeg A, Ilgen, P., Bates M. and Jakobs S.: "Endogenous BAX and BAK form mosaic rings of variable size and composition on apoptotic mitochondria"
Cell Death Differ. DOI 10.1038/s41418-024-01273-xDetails
Lange F., Ratz M., Dohrke J.- N., Wenzel D., Ilgen P., Riedel D., Jakobs S.: "In-situ architecture of the human prohibitin complex"
bioRxiv. DOI 10.1101/2024.02.14.579514Details
Stephan T., Stoldt S., Barbot M., Carney T. D., Lange F., Bates M., Bou Dib P., Inamdar K., Shcherbata H. R., Meinecke M., Riedel D., Dennerlein S., Rehling P., Jakobs S.: "Drosophila MIC10b can polymerize into cristae-shaping filaments"
Life Science Alliance 7 (4), e202302177. DOI 10.26508/lsa.202302177Details
Hintze A., Lange F., Steyer M. A., Anstatt J., Möbius W., Jakobs S.*, Wichmann C.*: "Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus"
iScience 27 (1). DOI 10.1016/j.isci.2023.108700. (*shared corresponding authors)Details
2023
Schweighofer S. V., Jans D. C., Keller-Findeisen J., Folmeg A., Bates M., Jakobs S.: "Endogenous BAX and BAK form mosaic rings of variable size and composition on apoptotic mitochondria"
bioRxiv. DOI 10.1101/2023.08.18.553869Details
Michanski S., Henneck T., Mukhopadhyay M., Steyer A. M., Agüi Gonzalez P., Grewe K., Ilgen P., Gültas M., Fornasiero E. F., Jakobs S., Möbius W., Vogl C., Pangršič T., Rizzoli S. O., Wichmann C.: "Age-dependent structural reorganization of utricular ribbon synapses"
Front. Cell Dev. Biol. 11. DOI 10.3389/fcell.2023.1178992Details
Ebrahimi V., Stephan T., Kim J., Carravilla P., Eggeling C., Jakobs S. and Han K. Y.: "Deep learning enables fast, gentle STED microscopy"
Commun. Biol. 6 (674). DOI 10.1038/s42003-023-05054-zDetails
Stephan T., Stoldt S., Barbot M., Carney T. D., Lange F., Bates M., Bou Dib P., Shcherbata H. R., Meinecke M., Riedel D., Dennerlein S., Rehling P., Jakobs S.: "The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments"
bioRxiv. DOI 10.1101/2023.04.17.537183Details
Kim D., Stoldt S., Weber M., Jakobs S., Belov V. N., Hell S. W.: "A Bright Surprise: Live-Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag"
Chem. Eur. J. 3 (9). DOI 10.1002/cmtd.202200076Details
Ebrahimi V., Stephan T., Kim J., Carravilla P., Eggeling C., Jakobs S., Young Han K.: "Deep learning enables fast, gentle STED microscopy"
bioRxiv. DOI 10.1101/2023.01.26.525571Details
2022
Michanski S., Henneck T., Mukhopadhyay M., Steyer A. M., Agüi Gonzalez P., Grewe K., Ilgen P., Gültas M., Fornasiero E. F., Jakobs S., Möbius W., Vogl C., Pangršič T., Rizzoli S. O., Wichmann C.: "Age-dependent structural reorganization of utricular ribbon synapses"
bioRxiv. DOI 10.1101/2022.12.19.521049Details
Liu T., Stephan T., Chen P., Keller-Findeisen J., Chen J., Riedel D., Yang Z., Jakobs S. and Chen Z.: "Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain"
PNAS 119 (52). DOI 10.1073/pnas.2215799119Details
Stejerean-Todoran I., Zimmermann K., Gibhardt Adina Vultur C. S., Ickes C., Shannan B., Bonilla del Rio Z., Wölling A., Cappello S., Sung H. -M., Shumanska M., Zhang X., Nanadikar M., Latif M. U., Wittek A., Lange F., Waters A., Brafford P., Wilting J., Urlaub H., Katschinski D. M., Rehling P., Lenz C., Jakobs S., Ellenrieder V., Roesch A., Schön M. P., Herlyn M., Stanisz H., Bogeski I.: "MCU controls melanoma progression through a redox-controlled phenotype switch"
EMBO Reports e54746 (23). DOI 10.15252/embr.202254746Details
Bock-Bierbaum T., Funck K., Wollweber F., Lisicki E., von der Malsburg K., von der Malsburg A., Laborenz J., Noel J. K., Hessenberger M., Jungbluth S., Bernert C., Kunz S., Riedel D., Lilie H., Jakobs S., van der Laan M., Daumke O.: "Structural insights into crista junction formation by the Mic60-Mic19 complex"
ScienceAdvances 8 (35). DOI 10.1126/sciadv.abo4946Details
Ostersehlt L. M., Jans D. C., Wittek A., Keller-Findeisen J., Inamdar K., Sahl S.J., Hell S. W., Jakobs S.: "DNA-PAINT MINFLUX nanoscopy"
Nature Methods 19, 1072-1075. DOI 10.1038/s41592-022-01577-1Details
Adam V., Hadjidemetriou K., Jensen N., Shoeman R. L., Woodhouse J., Aquila A., Banneville A.-S., Barends T. R. M., Bezchastnov V., Boutet S., Byrdin M., Cammarata M., Carbajo S., Christou N. E., Coquelle N., De la Mora E., El Khatib M., Moreno Chicano T., Doak R. B., Fieschi F., Foucar L., Glushonko O., Gorel A., Grünbein M. L., Hilpert M., Hunter M., Kloos M., Koglin J. E., Lane T. J., et al.: "Rational Control of Off-State Heterogeneity in a Photoswitchable Fluorescent Protein Provides Switching Contrast Enhancement"
ChemPhysChem 23 (19). DOI 10.1002/cphc.202200192Details
Bates M., Keller-Findeisen J., Przybylski A., Hüper A., Stephan T., Ilgen P., Cereceda Delgado A. R., D’Este E., Egner A., Jakobs S., Sahl S. J., Hell S. W.: "Optimal precision and accuracy in 4Pi-STORM using dynamic spline PSF models"
Nature Methods 19, 603–612. DOI 10.1038/s41592-022-01465-8Details
Liu T., Stephan T., Chen P., Chen J., Riedel D., Yang Z., Jakobs S., Zhixing Chen Z.: "Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane strain"
bioRxiv. DOI 10.1101/2022.05.09.491019Details
Bock-Bierbaum T., Funck K., Wollweber F., Lisicki E., Laborenz J., Noel J. K., Hessenberger M., von der Malsburg A., von der Malsburg K., Bernert C., Kunz S., Riedel D., Lilie H., Jakobs S., van der Laan M., Daumke O.: "Structural insights into crista junction formation by the Mic60-Mic19 complex"
bioRxiv. DOI 10.1101/2022.03.30.486340Details
2021
Dennerlein S., Poerschke S., Oeljeklaus S., Wang C., Richter-Dennerlein R., Sattmann J., Bauermeister D., Hanitsch E., Stoldt S., Langer T., Jakobs S., Warscheid B., Rehling P.: "Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors."
eLIFE 10, e68213. DOI 10.7554/eLife.68213Details
Brüser C., Keller-Findeisen J., Jakobs S.: "The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels"
Cell Reports 37, e110000. DOI 10.1016/j.celrep.2021.110000Details
Gomkale R., Linden A., Neumann P., Schendzielorz A.B., Stoldt S., Dybkov O., Kilisch M., Schulz C., Cruz-Zaragoza L.D., Schwappach B., Ficner R., Jakobs S., Urlaub H., Rehling P.: "Mapping protein interactions in the active TOM-TIM23 supercomplex"
Nature Communications 12, 5715. DOI 10.1038/s41467-021-26016-1Details
Siegmund R., Werner F., Jakobs S., Geisler C., Egner A.: "isoSTED microscopy with water-immersion lenses and background reduction"
Biophysical Journal 120 (16). DOI https://doi.org/10.1016/j.bpj.2021.05.031Details
Bollmann F., Dohrke J.-N., Wurm Ch.A., Jans D.C., Jakobs S.: "Mitochondrial Protein Abundance Gradients Require the Distribution of Separated Mitochondria"
Biology 10 (7). DOI https://doi.org/10.3390/biology10070572Details
Konen T., Stumpf D., Grotjohann T., Jansen I., Bossi M., Weber M., Jensen N., Hell S. W., Jakobs S.: "The Positive Switching Fluorescent ProteinPadron2 Enables Live-Cell ReversibleSaturable Optical Linear FluorescenceTransitions (RESOLFT) Nanoscopy withoutSequential Illumination Steps"
ACS Nano 15 (6), 9509–9521. DOI 10.1021/acsnano.0c08207Details
Lange F., Agüi-Gonzalez P., Riedel D., Phan N.T.N., Jakobs S., Rizzoli S. O.: "Correlative fluorescence microscopy, transmission electron microscopy and secondary ion mass spectrometry (CLEM-SIMS) for cellular imaging"
PLoS One 16 (5). DOI 10.1371/journal.pone.0240768Details
Yousefi R., Fornasiero E.F., Cyganek l., Montoya J., Jakobs S., Rizzoli S.O., Rehling P., Pacheu‐Grau D.: "Monitoring mitochondrial translation in living cells"
EMBO Reports 22 (4), e51635. DOI 10.15252/embr.202051635Details
Tameling C., Stoldt S., Stephan T., Naas J., Jakobs S. & Munk A.: "Colocalization for super-resolution microscopy via optimal transport"
Nature Computational Science 1, 199–211. DOI 10.1038/s43588-021-00050-x. Article in News & ViewsDetails
Stephan T., Ilgen P., Jakobs S.: "Innenarchitektur der Zellkraftwerke – Membranfalten in Hochauflösung"
BIOspektrum 27. DOI 10.1007/s12268-021-1543-2Details
Weber M., Leutenegger M., Stoldt S., Jakobs S., Mihaila T.S., Butkevich A.N. and Hell S.W.: "MINSTED fluorescence localization and nanoscopy"
Nature Photonics 15, 361-366. DOI 10.1038/s41566-021-00774-2Details
2020
Ruhlandth D., Andresen M., Jensen N., Gregor I., Jakobs S., Enderlein J., Chizhik A.: "Absolute quantum yield measurements of fluorescent proteins using a plasmonic nanocavity"
Communications Biology 3, 627. DOI 10.1038/s42003-020-01316-2Details
Schnorrenberg S., Ghareeb H., Frahm L., Grotjohann T., Jensen N., Teichmann T., Hell S.W., Lipka V., Jakobs S.: "Live‐cell RESOLFT nanoscopy of transgenic Arabidopsis thaliana"
Plant Direct 4 (9), e00261. DOI 10.1002/pld3.261Details
Pape J.K., Stephan T., Balzarotti F., Büchner R., Lange F., Riedel D., Jakobs S.*, and Hell S.W.*: "Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins"
Proc. Natl. Acad. Sci. USA 117 (34), 20607-20614. DOI 10.1073/pnas.2009364117. (*shared corresponding authors) Highlighted in PNASDetails
Stephan T., Brüser C., Deckers M., Steyer A. M., Balzarotti F., Barbot M., Behr T. S., Heim G., Hübner W., Ilgen P., Lange F., Pacheu‐Grau D., Pape J. K., Stoldt S., Huser T., Hell S. W., Möbius W., Rehling P., Riedel D., Jakobs S.: "MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation"
The EMBO Journal, e104105. DOI https://doi.org/10.15252/embj.2019104105. Comment in EMBO JournalDetails
Jensen N., Jansen I., Kamper M., Jakobs S.: "Reversibly Switchable Fluorescent Proteins for RESOLFT Nanoscopy"
Nanoscale Photonic Imaging;Topics Applied Physics 134, 241-261. DOI https://doi.org/10.1007/978-3-030-34413-9_9Details
Jakobs S., Stephan T., Ilgen P., Brüser C.: "Light Microscopy of Mitochondria at the Nanoscale."
Annual Review of Biophysics 49, 289-308. DOI 10.1146/annurev-biophys-121219-081550Details
Woodhouse J., Kovacs G.N., Coquelle N., Uriarte L., Adam V., Barends T.R.M., Byrdin M., De La Mora E., Doak R., Feliks M., Field M., Fieschi F., Guillon V., Jakobs S., Joti Y., Macheboeuf P., Motomura K., Nass K., Owada S., Roome C., Ruckebusch C., Schiro G., Shoeman R., Thepaut M., Togashi T., Tono K., Yabashi M., Cammarata M., FoucarL., Bourgeois D., SliwaM.,Colletier J.P.,Schlichting I., WeikW.: "Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy"
Nature Communications 11. DOI 10.1038/s41467-020-14537-0Details
Toth A., Meyrat A., Stoldt S., Santiago R., Wenzel D., Jakobs S., von Ballmoos C., Ott M.: "Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes"
Proc. Natl. Acad. Sci. USA 117, 2412-2421. DOI 10.1073/pnas.1917968117Details
2019
Stephan T., Roesch A., Riedel D., Jakobs S.: "Live-cell STED nanoscopy of mitochondrial cristae"
Scientific Reports 9, 12419. DOI 10.1038/s41598-019-48838-2. Access the Publication via
This publication is one of the Top 100 downloaded Scientific Reports articles in Cell and Molecular Biology of 2019!Details
Wurm C.A., Schwarz H., Jans D.C., Riedel D., Humbel B.M., Jakobs S.: "Correlative STED super-resolution light and electron microscopy on resin sections"
Journal of Physics D: Applied Physics 52. DOI 10.1088/1361-6463/ab2b31Details
Frahm L., Keller-Findeisen J., Alt P., Schnorrenberg S., del Alamo Ruiz M., Aspelmeier T., Munk A., Jakobs S., Hell S.W.: "Molecular contribution function in RESOLFT nanoscopy"
Optics Express 27, 21956-21987. DOI 10.1364/OE.27.021956Details
Ramos E.S., Motori E., Brüser C., Kühl I., Yeroslaviz A., Ruzzenente B., Kauppila J.H., Busch J.D., Hultenby K., Habermann B.H., Jakobs S., Larsson N.G., Mourier A.: "Mitochondrial fusion is required for regulation of mitochondrial DNA replication"
PLOS Genetics 15, e1008085. DOI 10.1371/journal.pgen.1008085Details
Callegari S., Müller T., Schulz C., Lenz C., Jans D.C., Wissel M., Opazo F., Rizzoli S.O., Jakobs S., Urlaub H., Rehling P., Deckers M.: "A MICOS-TIM22 Association Promotes Carrier Import into Human Mitochondria."
Journal of Molecular Biology 431, 2835-2851. DOI 10.1016/j.jmb.2019.05.015Details
Stoldt S., Stephan T., Jans D.C., Brüser C., Lange F., Keller-Findeisen J., Riedel D., Hell S.W., Jakobs S.: "Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria"
Proc. Natl. Acad. Sci. USA 116, 9853-9858. DOI 10.1073/pnas.1820364116Details
Tuijtel M.W., Koster A.J., Jakobs S., Faas F.G.A., Sharp T.H.: "Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins"
Scientific Reports 9, 1369. DOI 10.1038/s41598-018-37728-8Details
Richter F., Dennerlein S., Nikolov M., Jans D.C., Naumenko N., Aich A., MacVicar T., Linden A., Jakobs S., Urlaub H., Langer T., Rehling P.: "ROMO1 is a constituent of the human presequence translocase required for YME1L protease import"
Journal of Cell Biology 218, 598-614. DOI 10.1083/jcb.201806093Details
2018
Kamper M., Ta H., Jensen N.A., Hell S.W., Jakobs S.: "Near-infrared STED nanoscopy with an engineered bacterial phytochrome"
Nature Communications 9, 4762. DOI 10.1038/s41467-018-07246-2. Access the Publication via Details
Stoldt S., Wenzel D., Kehrein K., Riedel D., Ott M., Jakobs S.: "Spatial orchestration of mitochondrial translation and OXPHOS complex assembly"
Nature Cell Biology 20, 528–534. DOI 10.1038/s41556-018-0090-7. Access the Publication via
Comment in Nature Cell Biology.Details
Butkevich A.N., Ta H., Ratz M., Stoldt S., Jakobs S., Belov V.N., Hell S.W.: "Two-Color 810 nm STED Nanoscopy of Living Cells with Endogenous SNAP-Tagged Fusion Proteins."
ACS Chemical Biology 13, 475-480. DOI 10.1021/acschembio.7b00616Details
Faoro F., Bassu M., Mejia Y.X., Stephan T., Dudani N., Boeker S., Jakobs S., Burg T.P.: "Aberration-corrected cryoimmersion light microscopy"
Proc. Natl. Acad. Sci. USA 115, 1204-1209. DOI 10.1073/pnas.1717282115Details
Coquelle N., Sliwa M., Woodhouse J., Schiro G., Adam V., Aquila A., Barends T., Boutet S., Byrdin M., Carbajo S., de la Mora E., Doak Feliks M., Fieschi F., Foucar L., Guillon V., Hilpert M., Hunter M., Jakobs S., Koglin J., Kovacsova G., Lane T., Lévy B., Liang M., Nass K., Ridard J., Robinson J., Roome C., Ruckebusch C., Seaberg M., Thepaut M., Cammarata M., Demac: "Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography"
Nature Chemistry 10, 31-37. DOI 10.1038/nchem.2853Details
2017
Sahl S.J., Hell S.W., Jakobs S.: "Fluorescence nanoscopy in cell biology"
Nature Reviews Molecular Cell Biology 18, 685-701. DOI 10.1038/nrm.2017.71. Access the Publication via Details
Tarasenko D., Barbot M., Jans D.C., Kroppen B., Sadowski B., Heim G., Möbius W., Jakobs S., Meinecke M.: "The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology"
Journal of Cell Biology 216, 889-899. DOI 10.1083/jcb.201609046Details
Chmyrov A., Leutenegger M., Grotjohann T., Schönle A., Keller-Findeisen J., Kastrup L., Jakobs S., Donnert G., Sahl S.J., Hell S.W.: "Achromatic light patterning and improved image reconstruction for parallelized RESOLFT nanoscopy"
Scientific Reports 7, 44619. DOI 10.1038/srep44619Details
2016
Danzl J.G., Sidenstein S.C., Gregor C., Urban N.T., Ilgen P., Jakobs S., Hell S.W.: "Coordinate-targeted fluorescence nanoscopy with multiple off states"
Nature Photonics 10, 122-128. DOI 10.1038/nphoton.2015.266. Journal Cover Nature Photonics Feb. 2016.
Highlighted in Nature Methods.Details
Sahl S.J., Balzarotti F., Keller-Findeisen J., Leutenegger M., Westphal V., Egner A., Lavoie-Cardinal F., Chmyrov A., Grotjohann T., Jakobs S.: "Comment on “Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics”"
Science 352, 527. DOI 10.1126/science.aad7983Details
Schnorrenberg S., Grotjohann T., Vorbrüggen G., Herzig A., Hell S.W., Jakobs S.: "In vivo super-resolution RESOLFT microscopy of Drosophila melanogaster"
eLIFE 5, e15567. DOI 10.7554/eLife.15567. Highlighted in Nature Methods.Details
Große L., Wurm C.A., Brüser C., Neumann D., Jans D.C., Jakobs S.: "Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis"
The EMBO Journal 35, 402-413. DOI 10.15252/embj.201592789. Highlighted in The EMBO Journal.
Journal Cover EMBO Journal Feb. 2016.
Details
Callegari S., Richter F., Chojnacka K., Jans D.C., Lorenzi I., Pacheu-Grau D., Jakobs S., Lenz C., Urlaub H., Dudek J., Chacinska A., Rehling P.: "TIM29 is a subunit of the human carrier translocase required for protein transport"
FEBS Letters 590, 4147–4158. DOI 10.1002/1873-3468.12450Details
2015
Walter A., Andresen M., Jakobs S., Schroeder J., Schwarzer D.: "Primary Light-Induced Reaction Steps of Reversibly Photoswitchable Fluorescent Protein Padron0.9 Investigated by Femtosecond Spectroscopy"
The Journal of Physical Chemistry B119, 5136–5144. DOI 10.1021/jp512610qDetails
Kehrein K., Schilling R., Möller-Hergt B.V., Wurm C.A., Jakobs S., Lamkemeyer T., Langer T., Ott, M.: "Organization of Mitochondrial Gene Expression in Two Distinct Ribosome-Containing Assemblies"
Cell Reports 10, 843–853. DOI 10.1016/j.celrep.2015.01.012Details
Ratz M., Testa I., Hell S.W., Jakobs S.: "CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells"
Scientific Reports 5, 9592. DOI 10.1038/srep09592. This publication is one of the Top 100 read Scientific Reports articles in 2015!
Details
Barbot M., Jans D.C., Schulz C., Denkert N., Koppen B., Hoppert M., Jakobs S., Meinecke M.: "Mic10 Oligomerizes to Bend Mitochondrial Inner Membranes at Cristae Junctions"
Cell Metabolism 21, 756-763. DOI 10.1016/j.cmet.2015.04.006. Highlighted in Cell Metab. 2015 May 5;21(5):660-1.Details
Kukat C., Davies K.M., Wurm C.A., Spåhr H., Bonekamp N.A., Kühl I., Joos F., Polosa P.L., Park C.B., Posse V., Falkenberg M., Jakobs S., Kühlbrandt W., Larsson N.G.: "Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid."
Proc. Natl. Acad. Sci. USA 112, 11288-93. DOI 10.1073/pnas.1512131112Details
Dennerlein S., Oeljeklaus S., Jans D.C., Hellwig C., Bareth B., Jakobs S., Deckers M., Warscheid B., Rehling P.: "MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly."
Cell Reports 12, 1644-55. DOI 10.1016/j.celrep.2015.08.009Details
Duwé S., De Zitter E., Gielen V., Moeyaert B., Vandenberg W., Grotjohann T., Clays K., Jakobs S., Van Meervelt L., Dedecker P.: "Expression-Enhanced Fluorescent Proteins Based on Enhanced Green Fluorescent Protein (EGFP) for Super-Resolution Microscopy."
ACS Nano 10, 9528–9541. DOI 10.1021/acsnano.5b04129Details
Ilgen P., Grotjohann T., Jans D.C., Kilisch M., Hell S.W., Jakobs S.: "RESOLFT Nanoscopy of Fixed Cells Using a Z-Domain Based Fusion Protein for Labelling"
PLoS One 10, e0136233. DOI 10.1371/journal.pone.0136233Details
Sakowska P., Jans D.C., Mohanraj K., Riedel D., Jakobs S., Chacinska A.: "The oxidation status of Mic19 regulates MICOS assembly"
Molecular and Cellular Biology 35, 4222-4237. DOI 10.1128/MCB.00578-15Details
Hell S.W., Sahl S.J., Bates M., Zhuang X., Heintzmann R., Booth M.J., Bewersdorf J., Shtengel G., Hess H., Tinnefeld P., Honigmann A., Jakobs S., Testa I., Cognet L., Lounis B., Ewers H., Davis S.J., Eggeling C., Klenerman D., Willig K.I., Vicidomini G., Castello M.: "The 2015 super-resolution microscopy roadmap"
Journal of Physics D: Applied Physics 48, 443001. DOI doi:10.1088/0022-3727/48/44/443001Details
2014
Jensen N.A., Danzl J.G., Willig K.I., Lavoie-Cardinal F., Brakenmann T., Hell S.W., Jakobs S.: "Coordinate-Targeted and Coordinate-Stochastic Super-Resolution Microscopy with the Reversibly Switchable Fluorescent Protein Dreiklang"
ChemPhysChem 15, 756-762. DOI 10.1002/cphc.201301034Details
Lavoie-Cardinal F., Jensen N.A., Westphal V., Stiel A.C., Chmyrov A., Bierwagen J., Testa I., Jakobs S., Hell S.W.: "Two-Color RESOLFT Nanoscopy with Green and Red Fluorescent Photochromic Proteins"
ChemPhysChem 15, 655-663. DOI 10.1002/cphc.201301016. Journal Cover ChemPhysChem Mar. 2014.Details
Pfanner N., van der Laan M., Amati P., Capaldi R.A., Caudy A.A., Chacinska A., Darshi M., Deckers M., Hoppins S., Icho T., Jakobs S., Ji J., Kozjak-Pavlovic V., Meisinger C., Odgren P.R., Park S.K., Rehling P., Reichert A.S., Sheikh M.S., Taylor S.S., Tsuchida N., van der Bliek A.M., van der Klei I.J., Weissman J.S., Westermann B., Zha J., Neupert W., Nunnari J.: "Uniform nomenclature for the mitochondrial contact site and cristae organizing system"
Journal of Cell Biology 204, 1083-1086. DOI 10.1083/jcb.201401006Details
Ilgen P., Stoldt S., Conradi L.C., Wurm C.A., Rüschoff J., Ghadimi B.M., Liersch T., Jakobs S.: "STED Super-Resolution Microscopy of Clinical Paraffin-Embedded Human Rectal Cancer Tissue"
PLoS ONE 9, e101563. DOI 10.1371/journal.pone.0101563Details
Jakobs S., Wurm C.A.: "Super-resolution microscopy of mitochondria"
Current Opinion in Chemical Biology 20, 9–15. DOI 10.1016/j.cbpa.2014.03.019Details
Geissbuehler S., Sharipov A., Godinat A., Bocchio N.L., Sandoz P.A., Huss A., Jensen N.A., Jakobs S., Enderlein J., van der Goot F.G., Dubikovskaya E.A., Lasser T., Leutenegger M.: "Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging"
Nature Communications 5. DOI 10.1038/ncomms6830Details
2013
Chmyrov A., Keller J., Grotjohann T., Ratz M., d`Este E., Jakobs S., Eggeling C., Hell S.W.: "Nanoscopy with more than 100,000 'doughnuts'"
Nature Methods 10, 737-740. DOI 10.1038/nmeth.2556. Highlighted in Nature Methods.
Journal Cover Nature Methods Aug. 2013.Details
Jans D.C., Wurm C.A., Riedel D., Wenzel D., Stagge F., Deckers M., Rehling R., Jakobs S.: "STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria"
Proc. Natl. Acad. Sci. USA 110, 8936-8941. DOI 10.1073/pnas.1301820110Details
Stagge A., Mitronova G.Y., Belov V.B., Wurm C.A., Jakobs, S.: "Snap-, CLIP- and Halo-Tag Labelling of Budding Yeast Cells"
PLoS One 8, e78745. DOI 10.1371/journal.pone.0078745Details
2012
Wurm C. A., Kolmakov K., Göttfert F., Ta H., Bossi M., Schill H., Berning S., Jakobs S., Donnert G., Belov V. N., Hell S. W.: "Novel red fluorophores with superior performance in STED microscopy"
Optical Nanoscopy 1 (7). DOI 10.1186/2192-2853-1-7Details
Alkhaja A.K., Jans D.C., Nikolov M., Vukotic M., Lytovchenko O., Ludewig F., Schliebs W., Riedel D., Urlaub H., Jakobs S., Deckers M.: "MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization"
Molecular Biology of the Cell 23, 247-257. DOI 10.1091/mbc.E11-09-0774Details
Grotjohann T., Testa I., Reuss M., Brakemann T., Eggeling C., Hell S.W., Jakobs S.: "rsEGFP2 enables fast RESOLFT nanoscopy of living cells"
ELife 1, e00248. DOI 10.7554/eLife.00248. Highlighted in The Scientist.Details
Kolmakov K., Wurm C.A., Hennig R., Rapp E., Jakobs S., Belov V.N., Hell S.W.: "Red-Emitting Rhodamines with Hydroxylated, Sulfonated, and Phosphorylated Dye Residues and Their Use in Fluorescence Nanoscopy"
Chemistry A European Journal 18, 12986-12998. DOI 10.1002/chem.201201168Details
Stoldt S., Wenzel W., Hildenbeutel M., Wurm C.A., Herrmann J.M., Jakobs S.: "The inner-mitochondrial distribution of Oxa1 depends on the growth conditions and on the availability of substrates"
Molecular Biology of the Cell 23, 2292-2301. DOI 10.1091/mbc.E11-06-0538Details
Testa I., Urban N.T., Jakobs S., Eggeling C., Willig K.I., Hell S.W.: "Nanoscopy of Living Brain Slices with Low Light Levels"
Neuron 75, 992-1000. DOI 10.1016/j.neuron.2012.07.028Details
Vukotic M., Oeljeklaus S., Wiese S., Vögtle N.F., Meisinger C., Meyer H.E., Zieseniss A., Katschinski D.M., Jans D.C., Jakobs S., Warscheid B., Rehling P., Deckers M.: "Rcf1 Mediates Cytochrome Oxidase Assembly and Respirasome Formation, Revealing Heterogeneity of the Enzyme Complex"
Cell Metabolism 15, 336-347. DOI 10.1016/j.cmet.2012.01.016. Highlighted in Cell Metabolism.Details
2011
Brakemann T., Stiel A.C., Weber G., Andresen M., Testa I., Grotjohann T., Leutenegger M., Plessmann U., Urlaub H., Eggeling C., Wahl M.C., Hell S.W.*, Jakobs S.*: "A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching"
Nature Biotechnology 29, 942-947. DOI 10.1038/nbt.1952. (*shared corresponding authors)
Highlighted in Nature Biotechnoloy.
Journal Cover Nature Biotechnology Oct. 2011.
Details
Grotjohann T., Testa I., Leutenegger M., Bock H., Urban N.T., Lavoie-Cardinal F., Willig K.I., Eggeling C., Jakobs S.*, Hell, S.W.*: "Diffraction-unlimited all-optical imaging and writing with a photochromic GFP"
Nature 478, 204-208. DOI 10.1038/nature10497. (*shared corresponding authors) Details
Jakobs S., Stoldt S., Neumann D.: "Light Microscopic Analysis of Mitochondrial Heterogeneity in Cell Populations and Within Single Cells"
Advances in Biochemical Engineering/Biotechnology 124, 1-19. DOI 10.1007/10_2010_81Details
Kleine-Vehn J., Wabnik K., Martiniere A., Langowski L., Willig K., Naramoto S., Leitner J., Tanaka H., Jakobs S., Robert S., Luschnig C., Govaerts W., Hell S.W., Runions J., Friml J.: "Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane"
Molecular Systems Biology 7, 540. DOI 10.1038/msb.2011.72Details
Kukat C.,Wurm C.A., Spahr H.,Falkenberg M., Larsson N., Jakobs S.: "Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA"
Proc. Natl. Acad. Sci. USA 108, 13534-13539. DOI 10.1073/pnas.1109263108Details
Willig K.I., Stiel A.C., Brakemann T., Jakobs S., Hell S.W.: "Dual-Label STED Nanoscopy of Living Cells Using Photochromism"
Nano Letters 11, 3970-3973. DOI 10.1021/nl202290wDetails
Wurm C.A., Neumann D., Lauterbach M.A., Harke B., Egner A., Hell S.W., Jakobs S.: "Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient"
Proc. Natl. Acad. Sci. USA 108, 13546-13551. DOI 10.1073/pnas.1107553108Details
2010
Bierwagen J., Testa I., Foelling J., Wenzel D., Jakobs S., Eggeling C., Hell S.W.: "Far-Field Autofluorescence Nanoscopy"
Nano Letters 10, 4249-4252. DOI 10.1021/nl1027638Details
Brakemann T., Weber G., Andresen M., Groenhof G., Stiel A.C., Trowitzsch S., Eggeling C., Grubmueller H., Hell S.W., Wahl M.C., Jakobs S.: "Molecular Basis of the Light-driven Switching of the Photochromic Fluorescent Protein Padron"
Journal of Biological Chemistry 285, 14603-14609. DOI 10.1074/jbc.M109.086314Details
Belov V.N., Wurm C.A., Boyarskiy V.P., Jakobs S., Hell S.W.: "Rhodamines NN: A Novel Class of Caged Fluorescent Dyes"
Angewandte Chemie - International Edition 49, 3520-3523. DOI 10.1002/anie.201000150. Highlighted in Nature Chemistry.
Journal Cover Angewandte Chemie Apr. 2010.Details
Hein B., Willig K.I., Wurm C.A., Westphal V., Jakobs S., Hell S.W.: "Stimulated Emission Depletion Nanoscopy of Living Cells Using SNAP-Tag Fusion Proteins"
Biophysical Journal 98, 158-163. DOI 10.1016/j.bpj.2009.09.053Details
Mitronova G.Y., Belov V.N., Bossi M.L., Wurm C.A., Meyer L., Medda R., Moneron G., Bretschneider S., Eggeling C., Jakobs S., Hell S.W.: "New Fluorinated Rhodamines for Optical Microscopy and Nanoscopy"
Chemistry A European Journal 16, 4477-4488. DOI 10.1002/chem.200903272Details
Neumann D., Buckers J., Kastrup L., Hell S.W., Jakobs S.: "Two-color STED microscopy reveals different degrees of colocalization between hexokinase-I and the three human VDAC isoforms"
PMC Biophysics 3. DOI 10.1186/1757-5036-3-4Details
Testa I., Wurm C.A., Medda R., Rothermel E., von Middendorf C., Foelling J., Jakobs S., Schoenle A., Hell S.W., Eggeling C.: "Multicolor Fluorescence Nanoscopy in Fixed and Living Cells by Exciting Conventional Fluorophores with a Single Wavelength"
Biophysical Journal 99, 2686-2694. DOI 10.1016/j.bpj.2010.08.012Details
Wurm, C.A.,Neumann, D.,Schmidt, R.,Egner, A. and Jakobs, S.: "Sample Preparation for STED Microscopy"
Live Cell Imaging: Methods and Protocols 591, 185-199. DOI 10.1007/978-1-60761-404-3_11Details
Wurm C.A., Suppanz I.E., Stoldt S., Jakobs, S.: "Rapid FlAsH labelling in the budding yeast Saccharomyces cerevisiae"
Journal of Microscopy 240, 6-13. DOI 10.1111/j.1365-2818.2010.03378.xDetails
2009
Schmidt R., Wurm C.A., Punge A., Egner A., Jakobs S., Hell S.W.: "Mitochondrial Cristae Revealed with Focused Light"
Nano Letters 9, 2508-2510. DOI 10.1021/nl901398t. Highlighted in Spiegel Online.Details
2008
Altmann K., Frank M., Neumann D., Jakobs S., Westermann, B.: "The class V myosin motor protein, Myo2, plays a major role in mitochondrial motility in Saccharomyces cerevisiae"
Journal of Cell Biology 181, 119-130. DOI 10.1083/jcb.200709099. Details
Andresen M., Stiel A.C., Foelling J., Wenzel D., Schoenle A., Egner A., Eggeling C., Hell S.W., Jakobs, S.: "Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy"
Nature Biotechnology 26, 1035-1040. DOI 10.1038/nbt.1493. Highlighted in Nature Methods and Nature Chemical Biology.
Details
Foelling J., Bossi M., Bock H., Medda R., Wurm C.A., Hein B., Jakobs S., Eggeling C., Hell S.W.: "Fluorescence nanoscopy by ground-state depletion and single-molecule return"
Nature Methods 5, 943-945. DOI 10.1038/nmeth.1257Details
Schmidt R., Wurm C.A., Jakobs S., Engelhardt J., Egner A., Hell S.W.: "Spherical nanosized focal spot unravels the interior of cells"
Nature Methods 5, 539-544. DOI 10.1038/nmeth.1214. Highlighted in Nature Methods.
Journal Cover Nature Methods Jun. 2008.Details
Stiel A.C., Andresen M., Bock H., Hilbert M., Schilde J., Schoenle A., Eggeling C., Egner A., Hell S.W., Jakobs S.: "Generation of monomeric reversibly switchable red fluorescent proteins for far-field fluorescence nanoscopy"
Biophysical Journal 95, 2989-2997. DOI 10.1529/biophysj.108.130146. Highlighted in Nature Methods.Details
Testa I., Schoenle A., Middendorff C., Geisler C., Medda R., Wurm C.A., Stiel A.C., Jakobs S., Bossi M., Eggeling C., Hell S.W., Egner A.: "Nanoscale separation of molecular species based on their rotational mobility"
Optics Express 16, 21093-21104. DOI 10.1364/oe.16.021093Details
Suppanz I.E., Wurm C.A., Wenzel D., Jakobs S.: "The m-AAA Protease Processes Cytochrome c Peroxidase Preferentially at the Inner Boundary Membrane of Mitochondria"
Molecular Biology of the Cell 20, 572-580. DOI 10.1091/mbc.E07-11-1112Details
2007
Andresen M., Stiel A.C., Trowitzsch S., Weber G., Eggeling C., Wahl M.C., Hell S.W., Jakobs, S.: "Structural basis for reversible photoswitching in Dronpa"
Proc. Natl. Acad. Sci. USA 104 (32), 13005-13009. DOI 10.1073/pnas.0700629104Details
Bock H., Geisler C., Wurm C.A., von Middendorff C., Jakobs S., Schönle A., Egner A., Hell S.W., Eggeling C.: "Two-color far-field fluorescence nanoscopy based on photoswitchable emitters"
Applied Physics B 88 (2), 161-165. DOI 10.1007/s00340-007-2729-0Details
Donnert G., Keller J., Wurm C.A., Rizzoli S.O., Westphal V., Schönle A., Jahn R., Jakobs S., Eggeling C., Hell S.W.: "Two-color far-field fluorescence nanoscopy"
Biophysical Journal 92 (8), L67-L69. DOI 10.1529/biophysj.107.104497. Details
Eggeling C., Hilbert M., Bock H., Ringemann C., Hofmann M., Stiel A.C., Andresen M., Jakobs S., Egner A., Schönle A., Hell S.W.: "Reversible photoswitching enables single-molecule fluorescence fluctuation Spectroscopy at high molecular concentration"
Microscopy Research and Technique 70 (12), 1003-1009. DOI 10.1002/jemt.20505Details
Egner A., Geisler C., von Middendorff C., Bock H., Wenzel D., Medda R., Andresen M., Stiel A.C., Jakobs S., Eggeling C., Schönle A., Hell S.W.: "Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters"
Biophysical Journal 93 (9), 3285-3290. DOI 10.1529/biophysj.107.112201Details
Meuer K., Suppanz I.E., Lingor P., Planchamp V., Göricke B., Fichtner L., Braus G.H., Dietz G.P.H., Jakobs S., Bähr M., Weishaupt J.H.: "Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis"
Cell Death and Differentiation 14 (4), 651-661. DOI 10.1038/sj.cdd.4402087Details
Schwentker M., Bock H., Hofmann M., Jakobs S., Bewersdorf J., Eggeling C., Hell S.W.: "Wide-field subdiffraction RESOLFT microscopy using fluorescent protein photoswitching"
Microscopy Research and Technique 70 (3), 269-280. DOI 10.1002/jemt.20443Details
Stiel A.C., Trowitzsch S., Weber G., Andresen M., Eggeling C., Hell S.W., Jakobs S., Wahl M.C.: "1.8 angstrom bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants"
Biochemical Journal 402, 35-42. DOI 10.1042/bj20061401Details
2006
Jakobs S.: "High resolution imaging of live mitochondria"
Biochimica et Biophysica Acta - Molecular Cell Res 1763 (5-6), 561-575. DOI 10.1016/j.bbamcr.2006.04.004Details
Medda R, Jakobs S., Hell S.W., Bewersdorf J.: "4Pi microscopy of quantum dot-labeled cellular structures"
Journal of Structural Biology 156 (3), 517-523. DOI 10.1016/j.jsb.2006.08.013Details
Schauss A.S., Bewersdorf J., Jakobs S.: "Fis1p and Caf4p, but not Mdv1p, determine the polar localization of Dnm1p clusters on the mitochondrial surface"
Journal of Cell Science 119 (15), 3098-3106. DOI 10.1242/jcs.03026Details
Willig K.I., Kellner R.R., Medda R., Jakobs S., Hell S.W.: "Nanoscale resolution in GFP-based microscopy"
Nature Methods 3 (9), 721-723. DOI 10.1038/nmeth922Details
Wurm C.A., Jakobs S.: "Differential protein distributions define two sub-compartments of the mitochondrial inner membrane in yeast"
FEBS Letters 580 (24), 5628-5634. DOI 10.1016/j.febslet.2006.09.012Details
Hell S. W., Willig K., Dyba M., Jakobs S., Kastrup L., & Westphal V.: "Nanoscale resolution with focused light: STED and other RESOLFT microscopy concepts."
Handbook Of Biological Confocal Microscopy 2006, 571 - 579. DOI 10.1007/978-0-387-45524-2_31Details
2005
Andresen M., Wahl M.C., Stiel A.C., Gräter F., Schäfer L.V., Trowitzsch S., Weber G., Eggeling C., Grubmüller H., Hell S.W., Jakobs S.: "Structure and mechanism of the reversible photoswitch of a fluorescent protein"
Proc. Natl. Acad. Sci. USA 102 (37), 13070-13074. DOI 10.1073/pnas.0502772102Details
Dimmer, K.S.,Jakobs, S.,Vogel, F.,Altmann, K. and Westermann, B.: "Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast"
J. Cell Biol. 168 (1), 103-115. DOI 10.1083/jcb.200410030. Details
Hofmann M., Eggeling C., Jakobs S., Hell S.W.: "Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins"
Proc. Natl. Acad. Sci. USA 102 (49), 17565-17569. DOI 10.1073/pnas.0506010102. Details
2004
Andresen M., Schmitz-Salue R., Jakobs S.: "Short tetracysteine tags to beta-tubulin demonstrate the significance of small labels for live cell imaging"
Molecular Biology of the Cell 15 (12), 5616-5622. DOI 10.1091/mbc.E04-06-0454Details
Gugel H., Bewersdorf J., Jakobs S., Engelhardt J., Storz R., Hell S.W.: "Cooperative 4Pi excitation and detection yields sevenfold sharper optical sections in live-cell microscopy"
Biophysical Journal 87 (6), 4146-4152. DOI 10.1529/biophysj.104.045815Details
Hell, S.W.,Dyba, M. and Jakobs, S.: "Concepts for nanoscale resolution in fluorescence microscopy"
Curr. Opin. Neurobiol. 14 (5), 599-609. DOI 10.1016/j.conb.2004.08.015Details
2003
Dyba, M.,Jakobs, S. and Hell, S.W.: "Immunofluorescence stimulated emission depletion microscopy"
Nature Biotech. 21 (11), 1303-1304. DOI 10.1038/nbt897. Journal Cover Nature Biotechnology Nov. 2003.Details
Hell, S.W.,Jakobs, S. and Kastrup, L.: "Imaging and writing at the nanoscale with focused visible light through saturable optical transitions"
Appl. Phys. A 77 (7), 859-860. DOI 10.1007/s00339-003-2292-4Details
Jakobs, S.,Martini, N.,Schauss, A.C.,Egner, A.,Westermann, B. and Hell, S.W.: "Spatial and temporal dynamics of budding yeast mitochondria lacking the division component Fis1p"
J. Cell Sci. 116 (10), 2005-2014. DOI 10.1242/jcs.00423Details
Jakobs, S.,Schauss, A.C. and Hell, S.W.: "Photoconversion of matrix targeted GFP enables analysis of continuity and intermixing of the mitochondrial lumens"
FEBS Letters 554 (1-2), 194-200. DOI 10.1016/s0014=5793(03)01170-0Details
Messerschmitt, M.,Jakobs, S.,Vogel, F.,Fritz, S.,Dimmer, K.S.,Neupert, W. and Westermann, B.: "The inner membrane protein Mdm33 controls mitochondrial morphology in yeast"
J. Cell Biol. 160 (4), 553-564. DOI 10.1083/jcb.200211113. Details
2002
Egner, A.,Jakobs, S. and Hell, S.W.: "Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast"
PNAS 99 (6), 3370-3375. DOI 10.1073/pnas.052545099Details
Kano, H.,Jakobs, S.,Nagorni, M. and Hell, S.W.: "Dual-color 4Pi-confocal microscopy with 3D-resolution in the 100 nm range"
Ultramicroscopy 90 (2-3), 207-213. DOI 10.1016/s0304-3991(01)00132-2Details
2001
Bahlmann, K.,Jakobs, S. and Hell, S.W.: "4Pi-confocal microscopy of live cells"
Ultramicroscopy 87 (3), 155-164. DOI 10.1016/s0304-3991(00)00092-9Details
2000
Dyba, M.,Klar, T.A.,Jakobs, S. and Hell, S.W.: "Ultrafast dynamics microscopy"
Appl. Phys. Lett. 77 (4), 597-599. DOI 10.1063/1.127056Details
Jakobs, S.,Subramaniam, V.,Schonle, A.,Jovin, T.M. and Hell, S.W.: "EGFP and DsRed expressing cultures of Escherichia coli imaged by confocal, two-photon and fluorescence lifetime microscopy"
FEBS Letters 479 (3), 131-135. DOI 10.1016/s0014-5793(00)01896-2Details
Klar, T.A.,Jakobs, S.,Dyba, M.,Egner, A. and Hell, S.W.: "Fluorescence microscopy with diffraction resolution barrier broken by stimulated emission"
PNAS 97 (15), 8206-8210. DOI 10.1073/pnas.97.15.8206. Highlighted in PNAS.Details